David C Dalgarno Selected Research

AP 24163

8/2009

9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation.

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David C Dalgarno Research Topics

Disease

7	Neoplasms (Cancer) 01/2016 - 09/2003
6	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2011 - 06/2006
5	Bone Diseases (Bone Disease) 10/2006 - 01/2002
4	Osteoporosis 10/2006 - 09/2003
3	Bone Resorption 10/2006 - 09/2003
1	Carcinogenesis 01/2016
1	Ovarian Neoplasms (Ovarian Cancer) 09/2006
1	Carcinoma (Carcinomatosis) 09/2006
1	Pathologic Processes 10/2004
1	Neoplasm Metastasis (Metastasis) 09/2003

Drug/Important Bio-Agent (IBA)

6	src-Family KinasesIBA 10/2006 - 01/2002
4	EnzymesIBA 01/2016 - 09/2003
4	Phosphotransferases (Kinase)IBA 06/2010 - 01/2002
3	Imatinib Mesylate (Gleevec)FDA Link 01/2011 - 06/2006
2	Adenosine Triphosphate (ATP)IBA 02/2013 - 09/2003
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2010 - 09/2006
2	Pharmaceutical PreparationsIBA 10/2006 - 09/2003
2	Diphosphonates (Bisphosphonates)IBA 10/2006 - 09/2003
1	Antineoplastic Agents (Antineoplastics)IBA 01/2016
1	Choline KinaseIBA 01/2016
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2016
1	Phosphorylcholine (Phosphocholine)IBA 01/2016
1	Lactate Dehydrogenase 5IBA 02/2013
1	Lactic Acid (Lactate)FDA LinkGeneric 02/2013
1	Dasatinib (BMS 354825)FDA Link 11/2009
1	nilotinib FDA Link 11/2009
1	ponatinibIBA 11/2009
1	AP 24163IBA 08/2009
1	Docetaxel (Taxotere)FDA Link 09/2006
1	AP23846IBA 09/2006
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 09/2006
1	LigandsIBA 09/2003
1	AP22408IBA 09/2003
1	PurinesIBA 09/2003
1	AP23236IBA 09/2003
1	Alendronate (Alendronate Sodium)FDA LinkGeneric 09/2003
1	Zoledronic Acid (Zometa)FDA Link 09/2003
1	Protein Kinases (Protein Kinase)IBA 01/2002

Therapy/Procedure

6	Therapeutics 01/2016 - 09/2003
1	Oral Administration 08/2009